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Synthesis of a new fluorine-18-labeled bexarotene analogue for PET imaging of retinoid X receptor

✍ Scribed by Wang, Min; Davis, Toni; Gao, Mingzhang; Zheng, Qi-Huang

Book ID
121679785
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
701 KB
Volume
24
Category
Article
ISSN
0960-894X

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A series of PET imaging studies were conducted with two fluorine-18-labeled tropane analoges, [(18)F](+)-FTT and [(18)F](+)-FCT. Both compounds possessed a high affinity and selectivity for the dopamine transporter and had a higher accumulation in the basal ganglia, a brain region having a high dens