Tomographic imaging of central nicotinic acetylcholine receptors (nAChRs) via single photon emission computed tomography (SPECT) has been hampered by the lack of a radioligand with suitable in vivo binding characteristics. Therefore, a novel analog of epibatidine, (6)-exo-2-(2-iodo-5-pyridyl)-7-azab
✦ LIBER ✦
Synthesis of a fluorine-18 labeled derivative of epibatidine for in vivo nicotinic acetylcholine receptor PET imaging
✍ Scribed by Lilian Dolci; Frédéric Dolle; Héric Valette; Françoise Vaufrey; Chantal Fuseau; Michel Bottlaender; Christian Crouzel
- Book ID
- 108480703
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 403 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0968-0896
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