𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and evaluation of fluorine-18 labelled compounds for imaging of bacterial infections with pet

✍ Scribed by S. Zijlstra; J. Gunawan; C. Freytag; W. Burchert


Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
153 KB
Volume
64
Category
Article
ISSN
0969-8043

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Fluorine-18 labelling of PNAs functional
✍ B. Kuhnast; F. Hinnen; R. Hamzavi; R. Boisgard; B. Tavitian; P. E. Nielsen; F. D 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 150 KB

## Abstract Peptide nucleic acids (PNAs) form a unique class of synthetic macromolecules, originally designed as ligands for the recognition of double‐stranded DNA, where the deoxyribose phosphate backbone of original DNA is replaced by a pseudo‐peptide __N__‐(2‐aminoethyl)glycyl backbone, while re

Synthesis and evaluation of two fluorine
✍ K. Serdons; D. Vanderghinste; M. Van Eeckhoudt; P. Borghgraef; H. Kung; F. Van L 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 368 KB

## Abstract Uncharged derivatives of thioflavin‐T have known __in vitro__ and __in vivo__ affinity for amyloid β. We synthesized and evaluated two derivatives with a fluorine‐18 labelled fluoropropoxy substituent either at the 6‐position or at the 2′‐position of the 2‐(4′‐aminophenyl)‐1,3‐benzothia

Design and synthesis of fluorine-18 labe
✍ Shozo Furumoto; Ren Iwata; Tatsuo Ido 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 130 KB

## Abstract Matrix metalloproteinases (MMPs) are key enzymes involved in cancer invasion and metastasis. New ^18^F‐labeled MMP inhibitors (**1a–c**) has been designed and synthesized for cancer imaging by positron emmision tomography. The precursors were synthesized in four steps starting from D‐fo

The traceless Staudinger ligation with f
✍ Marc Pretze; Frank Wuest; Tim Peppel; Martin Köckerling; Constantin Mamat 📂 Article 📅 2010 🏛 Elsevier Science 🌐 French ⚖ 511 KB

The development of rapid radiolabeling techniques under mild reaction conditions involving the shortlived positron emitter fluorine-18 remains a special challenge in organic PET chemistry. This work describes a novel and facile application of the traceless Staudinger ligation as a mild and versatile

Fluorine-18 labeling of 6,7-disubstitute
✍ Yann Seimbille; Michael E. Phelps; Johannes Czernin; Daniel H. S. Silverman 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 157 KB

Inhibitors of tyrosine kinase enzymatic activity represent a promising new class of antineoplastic agents. Although clinical studies performed over the last decade give more insight on the potential therapeutic applications of such drugs, identification of the individual patients who might benefit f