The design and synthesis of inhibitors o
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Rendina, Alan R; Taylor, Wendy S; Gibson, Katharine; Lorimer, George; Rayner, De
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Article
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1999
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John Wiley and Sons
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English
⚖ 246 KB
👁 2 views
Dethiobiotin synthetase (DTBS ; E.C. 6.6.6.6), the penultimate enzyme in the biosynthesis of the essential vitamin biotin, is a new potential target for novel herbicides. Inhibitors were designed based on mechanistic and structural information. The in-vitro activities of these potential inhibitors v