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Studies Towards the Synthesis of ATP Analogs as Potential Glutamine Synthetase Inhibitors

โœ Scribed by Salisu, Sheriff; Kenyon, Colin; Kaye, Perry T.


Book ID
126529993
Publisher
Taylor and Francis Group
Year
2011
Tongue
English
Weight
415 KB
Volume
41
Category
Article
ISSN
0039-7911

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Dethiobiotin synthetase (DTBS ; E.C. 6.6.6.6), the penultimate enzyme in the biosynthesis of the essential vitamin biotin, is a new potential target for novel herbicides. Inhibitors were designed based on mechanistic and structural information. The in-vitro activities of these potential inhibitors v