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Synthesis of dimethoxypyrimidines and uracils with novel C-5 substituents

โœ Scribed by Kundu, Nitya G.; Chaudhuri, Lakshmi N.


Book ID
111952670
Publisher
Royal Society of Chemistry
Year
1991
Weight
856 KB
Volume
7
Category
Article
ISSN
1472-7781

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A silicon-mediated synthesis of novel 5-
โœ Nitya G. Kundu; Biswajit Das; Anjali Majumdar; Lakshmi N. Choudhuri ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 256 KB

Sumnary: A highly efficient and general method for the synthesis of 5-(2-acylethynyl)-2,4dimethoxypyrimidines starting from 2,4-dimethoxy-5-/?r(brimethylsilyl)ethynyl~pyrimidine is described. The 5-(2-acylethynyl)-2,4-dimethoxypyrimidines have b?en converted to 5-(2-acyl-l-iodovinyl) uracils and 5-(