Studies on uracils: A simple and efficient method for the synthesis of novel pyrimido[4,5-c]pyridazines
β Scribed by Pulak J. Bhuyan; Kushal C Lekhok; Jagir S Sandhu
- Book ID
- 104260809
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 124 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The reaction of 6-hydrazino uracils 1 and acetylenedicarboxylates 2 at room temperature affords tetrahydro-pyrimido[4,5-c]pyridazines 3 in excellent yield.
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## Abstract Efficient and direct protocols for the regioselective synthesis of the title compounds (IV) and (IX), resp., using multicomponent reactions of 5βaminouracil (II) are given.