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Synthesis of deuterium-labeled acrivastine and an acrivastine metabolite

✍ Scribed by J. B. Thompson; K. W. Blake; R. W. McNutt

Publisher: John Wiley and Sons
Year: 1995
Tongue: French
Weight: 405 KB
Volume: 36
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580361009

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✦ Synopsis

Abstract

The antihistamine acrivastine and a metabolite dihydroacrivastine were prepared as their [^2^H~7~]‐congeners from [^2^H~8~]‐tolualdehyde for use as internal standards in gas chromatography/mass spectroscopy of biological samples.

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