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Synthesis of deuterated 4,4′-diaminodiphenylsulfone (Dapsone) and related analogs

✍ Scribed by Peter M. Gannett; Edward M. Johnson II; Michael A. Grimes; Alan L. Myers; Robert E. Deavers III; Timothy S. Tracy

Publisher
John Wiley and Sons
Year
2003
Tongue
French
Weight
97 KB
Volume
46
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

A general scheme for the synthesis of 4,4′‐diaminodiphenylsulfone‐d~5~ (Dapsone) from aniline‐d~5~ is described. The method may have general application and the preparation of the related analogs, 4,4′‐dimethylaminodiphenyl sulfone from aniline‐d~5~ and 4,4′‐dimethoxydiphenyl sulfone from phenol‐d~5~, is also described. Copyright © 2002 John Wiley & Sons, Ltd.

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