✦ LIBER ✦

Synthesis of chiral zileuton, a potent and selective inhibitor of 5-lipoxygenase

✍ Scribed by Chi-Nung Hsiao; Teodozyj Kolasa

Book ID: 108380359
Publisher: Elsevier Science
Year: 1992
Tongue: French
Weight: 250 KB
Volume: 33
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)79043-5

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis of the 5-lipoxygenase inhibito

Synthesis of the 5-lipoxygenase inhibitor zileuton from thiophenol

✍ Basha, Anwer; Brooks, Dee W. 📂 Article 📅 1993 🏛 American Chemical Society 🌐 English ⚖ 254 KB

The Discovery of Setileuton, a Potent an

The Discovery of Setileuton, a Potent and Selective 5-Lipoxygenase Inhibitor

✍ Ducharme, Yves; Blouin, Marc; Brideau, Christine; Châteauneuf, Anne; Gareau, Yv 📂 Article 📅 2010 🏛 American Chemical Society 🌐 English ⚖ 966 KB

Synthesis of CMI-977, a Potent 5-Lipoxyg

Synthesis of CMI-977, a Potent 5-Lipoxygenase Inhibitor †

✍ Cai, Xiong; Chorghade, Mukund S.; Fura, Aberra; Grewal, Gurmit S.; Jauregui, Kar 📂 Article 📅 1999 🏛 American Chemical Society 🌐 English ⚖ 103 KB

Synthesis and Structural Proof of a Pote

Synthesis and Structural Proof of a Potent 5-Lipoxygenase Inhibitor

✍ Devipriya Balu; Kumaradhas Poomani; Kalyanam Nagabushanam; Sridhar Balasubramani 📂 Article 📅 2011 🏛 Springer 🌐 English ⚖ 478 KB

ChemInform Abstract: Synthesis of CMI-97

ChemInform Abstract: Synthesis of CMI-977, a Potent 5-Lipoxygenase Inhibitor.

✍ Xiong Cai; Mukund S. Chorghade; Aberra Fura; Gurmit S. Grewal; Karen A. Jauregui 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

Synthesis of CMI-977, a Potent 5-Lipoxygenase Inhibitor. -A facile large-scale synthesis of the potent 5-lipoxygenase inhibitor CMI-977 (XI) in enantiomerically pure form starting from hydroxymethyl-γ-butyrolactone (I) derived from (S)-glutamic acid is described (yields given in g). -(CAI,

The discovery and development of zileuto

The discovery and development of zileuton: An orally active 5-lipoxygenase inhibitor

✍ R.L. Bell; P.R. Young; D. Albert; C. Lanni; J.B. Summers; D.W. Brooks; P. Rubin; 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 425 KB