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Synthesis of chelating molecules as agents for magnetic resonance imaging: 2. Synthesis and complexing properties of N-acryloyl diethyl iminodiacetate copolymers

✍ Scribed by Véronique Montembault; Véronique Folliot; Jean-Claude Soutif; Jean-Claude Brosse

Publisher
Elsevier Science
Year
1994
Weight
568 KB
Volume
22
Category
Article
ISSN
0923-1137

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✦ Synopsis

The synthesis of a monomer with diethyl iminodiacetate groups was investigated in order to obtain complexing copolymers. Copolymers of N-acryloyl diethyl iminodiacetate with acrylamide and acrylic acid were synthetized by a radical mechanism using 2,2'azobisisobutyronitrile (AIBN) as initiator in dioxane at 80°C. The compositions of the copolymers were established by 1H nuclear magnetic resonance (NMR) spectroscopy. The reactivity ratios were determined by both Fineman-Ross and Kelen-Tudos methods. The chelating ability of the synthetized copolymers was investigated with 152Eu.

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