✦ LIBER ✦

Synthesis of chelating molecules as agents for magnetic resonance imaging, 31. Polycondensation of diethylenetriaminepentaacetic acid bisanhydride with diols and diamines

✍ Scribed by Véronique Montembault; Jean-Claude Soutif; Jean-Claude Brosse

Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 918 KB
Volume: 29
Category: Article
ISSN: 1381-5148
DOI: 10.1016/1381-5148(96)00103-4

No coin nor oath required. For personal study only.

✦ Synopsis

The polycondensation of diethylenetriaminepentaacetic acid (DTPA) bisanhydride with diols and diamines was investigated in order to obtain new complexing agents bearing aminoacetic groups along the polymer chain whose complexing properties should be better than their monomolecular homologues: EDTA (ethylenediaminetetraacetic acid), DTPA . . .

Synthesis conditions have been studied to get linear water-soluble polymers destined to gadolinium complexation. Use of several types of comonomers has allowed us to obtain polycondensates having a varied density of COOH functions which will permit us to study its influence on their complexing properties towards different metallic cations.

📜 SIMILAR VOLUMES

Synthesis of chelating molecules as agen

Synthesis of chelating molecules as agents for magnetic resonance imaging: 2. Synthesis and complexing properties of N-acryloyl diethyl iminodiacetate copolymers

✍ Véronique Montembault; Véronique Folliot; Jean-Claude Soutif; Jean-Claude Brosse 📂 Article 📅 1994 🏛 Elsevier Science ⚖ 568 KB

The synthesis of a monomer with diethyl iminodiacetate groups was investigated in order to obtain complexing copolymers. Copolymers of N-acryloyl diethyl iminodiacetate with acrylamide and acrylic acid were synthetized by a radical mechanism using 2,2'azobisisobutyronitrile (AIBN) as initiator in di