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Synthesis of cembranoid analogues and evaluation of their potential as quorum sensing inhibitors

✍ Scribed by Edisson Tello; Leonardo Castellanos; Carmenza Duque

Book ID: 119203711
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 504 KB
Volume: 21
Category: Article
ISSN: 0968-0896
DOI: 10.1016/j.bmc.2012.10.022

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## Abstract The __gluco__‐configured analogue **15** of nagstatin (**1**) and the methyl ester **14** were synthesized __via__ condensation of the thionolactams **17** or **18** with the __β__‐amino ester **19**. The silyl ethers **20** and **21** resulting from **17** were desilylated to **22** an