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Synthesis of Nitrogen Analogues of Salacinol and Their Evaluation as Glycosidase Inhibitors

✍ Scribed by Ghavami, Ahmad; Johnston, Blair D.; Jensen, Morten T.; Svensson, Birte; Pinto, B. Mario

Book ID
124156747
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
65 KB
Volume
123
Category
Article
ISSN
0002-7863

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## Abstract The __gluco__‐configured analogue **15** of nagstatin (**1**) and the methyl ester **14** were synthesized __via__ condensation of the thionolactams **17** or **18** with the __Ξ²__‐amino ester **19**. The silyl ethers **20** and **21** resulting from **17** were desilylated to **22** an