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Synthesis and Evaluation of Sulfonium Analogues of Isofucofagomine as Glycosidase Inhibitors.

✍ Scribed by Victor Ulgar; Jose G. Fernandez-Bolanos; Mikael Bols


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
33
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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## Abstract The __gluco__‐configured analogue **15** of nagstatin (**1**) and the methyl ester **14** were synthesized __via__ condensation of the thionolactams **17** or **18** with the __Ξ²__‐amino ester **19**. The silyl ethers **20** and **21** resulting from **17** were desilylated to **22** an