Synthesis of New Nitrogen Analogues of Salacinol and Deoxynojirimycin and Their Evaluation as Glycosidase Inhibitors
β Scribed by Gallienne, Estelle; Gefflaut, Thierry; Bolte, Jean; Lemaire, Marielle
- Book ID
- 127196067
- Publisher
- American Chemical Society
- Year
- 2006
- Tongue
- English
- Weight
- 199 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The __gluco__βconfigured analogue **15** of nagstatin (**1**) and the methyl ester **14** were synthesized __via__ condensation of the thionolactams **17** or **18** with the __Ξ²__βamino ester **19**. The silyl ethers **20** and **21** resulting from **17** were desilylated to **22** an
India for financial support (Grant no. SP/S1/G-21/2001). We also thank Dr. D. D. Dhavale, Dr. S. G. Sabharwal, and Mr. Tarun Sharma of the University of Pune for help in carrying out the enzyme inhibition studies.