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Straightforward chemo-enzymatic synthesis of new aminocyclitols, analogues of valiolamine and their evaluation as glycosidase inhibitors

✍ Scribed by Lahssen El Blidi; Mustapha Ahbala; Jean Bolte; Marielle Lemaire


Book ID
111713802
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
174 KB
Volume
17
Category
Article
ISSN
0957-4166

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## Abstract The __gluco__‐configured analogue **15** of nagstatin (**1**) and the methyl ester **14** were synthesized __via__ condensation of the thionolactams **17** or **18** with the __Ξ²__‐amino ester **19**. The silyl ethers **20** and **21** resulting from **17** were desilylated to **22** an