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Synthesis and evaluation of thiazolidinedione and dioxazaborocane analogues as inhibitors of AI-2 quorum sensing in Vibrio harveyi

✍ Scribed by Brackman, Gilles; Al Quntar, Abed Al Aziz; Enk, Claes D.; Karalic, Izet; Nelis, Hans J.; Van Calenbergh, Serge; Srebnik, Morris; Coenye, Tom

Book ID
120456600
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
466 KB
Volume
21
Category
Article
ISSN
0968-0896

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## Abstract __Bacterial quorum sensing has received much attention in recent years because of its relevance to pathological events such as biofilm formation. Based on the structures of two lead inhibitors (IC~50~: 35–55β€…ΞΌM) against autoinducer‐2‐mediated quorum sensing identified through virtual sc