## Abstract Two labeled isotopomers of L‐tyrosine, L‐Tyr, have been synthesized using specific properties of the enzymes phenylanine ammonia lyase, PAL, and L‐phenylalanine hydroxylase. In an intermediate step [1‐^14^C]‐, and [2‐^14^C]‐L‐phenylalanine, L‐Phe, have been obtained from [1‐^14^C]‐, and
Synthesis of carbon-14 labelled l,5 diaryl-[5-14C]-l,2,3-triazolines
✍ Scribed by Hojatollah Matloubi; Abbas Shafiee; Nader Saemian; Gholamhossein Shirvani; Fariba Johari Daha
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- French
- Weight
- 81 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0022-2135
- DOI
- 10.1002/jlcr.794
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✦ Synopsis
Abstract
Two 1,2,3‐triazoline anticonvulsants, 1‐(4‐methylsulphone‐phenyl)‐5‐(4‐methoxy‐phenyl)‐1,2,3‐triazoline and l‐(4‐methylsulphone‐phenyl)‐5‐phenyl‐1,2,3‐triazoline, both labelled with carbon‐14 in the 5‐position, have been synthesized as part of a 5‐step sequence. Copyright © 2003 John Wiley & Sons, Ltd.
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## Abstract The synthesis of selectively ^14^C‐labeled l‐tryptophan and its derivative 5‐hydroxy‐l‐tryptophan using chemical and multienzymatic methods is reported. The mixture containing [1‐^14^C[‐dl‐alanine, indole or 5‐hydroxyindole has been converted to [1‐^14^C]‐l‐tryptophan or 5′‐hydroxy‐[1‐^