Double-lapgled PD-113,926 and CI-930 were synthesized from [ C]MeI and [ C]BaCO respectively in high specific activity (290 mCi/mmol). The &thesis of CI-930 employed the intermediate 2-b~tenenitrile-3,4-~'C which was synthesized by a phase transfer Wittig procedure. to good yields of olefin and acco
β¦ LIBER β¦
Synthesis of carbon-14 labeled PD 117,302 and PD 126,212, potential new analgesic agents
β Scribed by Sheryl J. Hays; James L. Hicks; Donald E. Butler; C. C. Huang
- Book ID
- 102372781
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- French
- Weight
- 389 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Two kappa opiate agonists 1 and 2 have been labeled from bromoβ[1β^14^C]βacetic acid and sodium [1β^14^C]acetate respectively.
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