๐”– Bobbio Scriptorium
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Synthesis of double carbon-14 labeled CI-9371 and CI-942, potential new anticancer drugs

โœ Scribed by James L. Hicks; C. C. Huang; H. D. Hollis Showalter


Book ID
102901085
Publisher
John Wiley and Sons
Year
1987
Tongue
French
Weight
526 KB
Volume
24
Category
Article
ISSN
0022-2135

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๐Ÿ“œ SIMILAR VOLUMES


Synthesis of carbon-14 labeled CI-926 an
โœ Sheryl J. Hays ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 400 KB

## 3-[4-~4-(3-Methylphenyl )-1-piperazinyllbutyl]-2,4-imidazolinedione, CI-926 (11, and 3-[[4-4-(3-ethoxyphenyl)-l-piperazinyl] butyl lamino] -5,5-dimethyl-2-cyclohexen-l -one, CI-927 (2) are new antihypertensive agents which have bee~~carbon-14 labeled in three steps starting from ethylene-C2 ox

Synthesis of high specific activity carb
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Double-lapgled PD-113,926 and CI-930 were synthesized from [ C]MeI and [ C]BaCO respectively in high specific activity (290 mCi/mmol). The &thesis of CI-930 employed the intermediate 2-b~tenenitrile-3,4-~'C which was synthesized by a phase transfer Wittig procedure. to good yields of olefin and acco