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Synthesis of carbon-11 labeled biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues as new potential PET glioma tumor imaging agents

✍ Scribed by Min Wang; Mingzhang Gao; Kathy D. Miller; George W. Sledge; Qi-Huang Zheng


Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
202 KB
Volume
65
Category
Article
ISSN
0969-8043

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## Abstract The tubulin polymerization is an attractive target for anticancer therapy and in the development of cancer imaging agents for use in biomedical imaging technique positron emission tomography (PET). 7‐Aroyl‐aminoindoline‐1‐sulfonamides are a novel class of potent antitublin agents. Carbo