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Synthesis of carbon-14 labeled 4-[4-[2-[2-[bis(4-chlorophenyl) methoxy]ethyl sulfonyl][1-14C]ethoxy]phenyl]-1,1,1-trifluoro-2-butanone

✍ Scribed by Douglas D. Dischino; Jacques Banville; Roger Remillard

Publisher
John Wiley and Sons
Year
2003
Tongue
French
Weight
91 KB
Volume
46
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Carbon‐14 labeled 4‐[4‐[2‐[2‐[bis(4‐chlorophenyl)methoxyethylsulfonyl] [1‐^14^C]ethoxy]phenyl]‐1,1,1‐trifluoro‐2‐butanone was prepared in a six step radioactive synthesis from 2‐bromo[1‐^14^C]acetic acid. The overall radiochemical yield was 2.2%. The specific activity of the final product was found to be 42μCi/mg with a radiochemical purity of >98%. Copyright © 2002 John Wiley & Sons, Ltd.

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