## Abstract **BACKGROUND:** The focus of this paper is the ultrasoundโassisted synthesis of caffeic acid phenethyl ester (CAPE) from caffeic acid and phenyl ethanol in a continuous packedโbed bioreactor. Immobilized Novozym^ยฎ^ 435 (from __Candida antarctica__) is used as the catalyst. A threeโlevel
Synthesis of Caffeic Acid Esters.
โ Scribed by Chun-nian Xia; Wei-xiao Hu
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 20 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Caffeic acid phenethyl ester (CAPE), which is derived from the propolis of honeybee hives, has been shown to block tumor promotion and to have toxic effects on several cancer cells. The mechanism of the antiโtumor promotion activity of CAPE is unclear, however. In this study, we found t