In this paper we report the synthesis of all-trans Retinoic acid, Retinal, Retinol specifically labelled with I4C at position 7 and all-trans Beta-carotene labelled at positions 7 and 7', with more than 98 % radiochemical purity. All products were obtained with about 15 % overall yield from I4C sodi
Synthesis of C15,C14′-ring locked all-trans-β-carotene
✍ Scribed by Pulgam Veera Reddy; Babak Borhan
- Book ID
- 104251081
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 101 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Synthesis of C15,14%-ring locked all-trans-b-carotene is described. The symmetric nature of the b-carotene analog allowed for rapid construction of the carbon frame through bis-olefination of the central dialdehyde containing the ring functionality with a C15 ylide bearing the ionone moiety.
📜 SIMILAR VOLUMES
A synthetic procedure for producing all trans [3A4C]menaquinone-4 is described The radiolabe is introduced using ethyl [3-'4C]acetoacetate as shown in the scheme. The final product has high chemical and radiochemical purity with a specific activity of 669 MBS/mnol. The overall radiochemical yield is
## Abstract The title compound (10) has been synthesized from all‐E‐2,7‐ dimethylocta‐2,4,6‐triene‐1,8‐dial (C~10~‐dialdehyde, 8) labelled with four ^13^C from commercially available and relatively inexpensive starting materials. The key starting material in this synthesis, (EtO)~2~P(O)^13^CHMe^13^
Synthesis of trans-2,2-Dimethyl-3-phenyl-4-(pppyrrolidinoethoxy)phenyl-7-rnethoxy-[2-Clchroman' 14 SUMMARY The synthesis of trans-2,2-dimethyl-3-phenyl-4-(~-~-pyrrolidinoethoxy) phenyl-7-metho~y-[2-~~C]chroman (Centchroman) , a post-coital antifertility agent from [l-14 Clphenylacetic acid is report