Tema~epam-2-'~C, 7-Chloro-1,3-ihydro-3-hydroxy-1 -methyl-5-phenyl-2H-1,4-benzodiazepin-2-one--"C, was prepared in a f ive-step synthesis. Chl~roacetic-l-~~C acid was converted to the acid chloride with thionyl chloride. The acid chloride was allowed to react with 2-methylamino-5-chloro-benzophenone
Synthesis of trans-2,2-Dimethyl-3-phenyl-4-(p-β-pyrrolidinoethoxy)phenyl-7-methoxy-[2-14C]chroman
✍ Scribed by P. L. Kole; Suprabhat Ray
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- French
- Weight
- 121 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Synthesis of trans-2,2-Dimethyl-3-phenyl-4-(pppyrrolidinoethoxy)phenyl-7-rnethoxy-[2-Clchroman' 14 SUMMARY The synthesis of trans-2,2-dimethyl-3-phenyl-4-(~-~-pyrrolidinoethoxy) phenyl-7-metho~y-[2-~~C]chroman (Centchroman) , a post-coital antifertility agent from [l-14 Clphenylacetic acid is reported.
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