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Synthesis of all-trans-beta-carotene retinoids and derivatives labelled with 14C

✍ Scribed by El-mostafa Azim; Philippe Auzeloux; Jean-Claude Maurizis; Véronique Braesco; Pascal Grolier; Annie Veyre; Jean-Claude Madelmont


Book ID
102659560
Publisher
John Wiley and Sons
Year
1996
Tongue
French
Weight
576 KB
Volume
38
Category
Article
ISSN
0022-2135

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✦ Synopsis


In this paper we report the synthesis of all-trans Retinoic acid, Retinal, Retinol specifically labelled with I4C at position 7 and all-trans Beta-carotene labelled at positions 7 and 7', with more than 98 % radiochemical purity. All products were obtained with about 15 % overall yield from I4C sodium cyanide. CCC 0362-4803/96/050441-11 01996 by John Wiley &Sons, Ltd.


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