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Synthesis of all trans [3′-14C]menaquinone-4

✍ Scribed by K. Shimada; K. Tadano; T. Satoh; K. Hashimoto; S. Tanaka; T. Yuzuriha

Publisher
John Wiley and Sons
Year
1989
Tongue
French
Weight
201 KB
Volume
27
Category
Article
ISSN
0022-2135

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✦ Synopsis

A synthetic procedure for producing all trans [3A4C]menaquinone-4 is described The radiolabe is introduced using ethyl [3-'4C]acetoacetate as shown in the scheme. The final product has high chemical and radiochemical purity with a specific activity of 669 MBS/mnol. The overall radiochemical yield is 12 % .

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