## Abstract The synthesis of new bioisosteric analogues of farnesyl pyrophosphate where a vinyl pyrophosphonate replaced the pyrophosphate moiety is described. These compounds have been prepared using a HornerβWadsworthβEmmons procedure and a modified Michelson reaction. They have been evaluated fo
β¦ LIBER β¦
Synthesis of C-11 Methyl-Substituted Benzocycloheptapyridine Inhibitors of Farnesyl Protein Transferase
β Scribed by Njoroge, F. George; Vibulbhan, Bancha; Wong, Jesse K.; White, Steven K.; Wong, Shing-Chun; Carruthers, Nicholas I.; Kaminski, James J.; Doll, Ronald J.; Girijavallabhan, V.; Ganguly, Ashit K.
- Book ID
- 125896707
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 90 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1523-7060
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