Synthesis of allylic amines through the palladium-catalyzed hydroamination of allenes
✍ Scribed by Laure Besson; Jacques Goré; Bernard Cazes
- Book ID
- 103408670
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 195 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Synthesis of potential antiparisitic 5'-aminonucloesides such as 10 could not be accomplished using standard amination procedures. Palladium(0)-catalyzed amination of cyclic allylic acetates with benzylamine or phthalimide gave the corresponding protected amines. This method was then extended to the
Substituted allenes are selectively obtained in good yields from the reaction of Grignard reagents with propargylic or allenic halides in the presence of catalytic amounts of palladium chloride, triphenylphosphine and diisobutyl aluminum hydride, in