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Regioselective synthesis of trifluoromethyl group substituted allylic amines via palladium-catalyzed allylic amination

โœ Scribed by Motoi Kawatsura; Takuya Hirakawa; Tomoko Tanaka; Daiji Ikeda; Shuichi Hayase; Toshiyuki Itoh


Book ID
108284859
Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
117 KB
Volume
49
Category
Article
ISSN
0040-4039

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Synthesis of protected allylic amines vi
โœ Nilantha S. Sirisoma; Patrick M. Woster ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 188 KB

Synthesis of potential antiparisitic 5'-aminonucloesides such as 10 could not be accomplished using standard amination procedures. Palladium(0)-catalyzed amination of cyclic allylic acetates with benzylamine or phthalimide gave the corresponding protected amines. This method was then extended to the