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Synthesis of active forms of vitamin D VI synthesis of (24R)- and (24S)-24,25-dihydroxyvitamin D3

✍ Scribed by Masao Seki; Naoyuki Koizumi; Masuo Morisaki; Nobuo Ikekawa

Publisher: Elsevier Science
Year: 1975
Tongue: French
Weight: 208 KB
Volume: 16
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)71765-5

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A synthesis of 25hydroxy [23,24JH]vitamin D3 leading to a radiochemically pure product with a specific activity of 78 Wmmol is described. The structure of the product was confirmed by comparison with unlabeled material and its biological activity was established by in vitro conversion to la,25dihydr