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Facile, stereoselective synthesis of (24R)-24,25-dihydroxyvitamin D3 using D-glyceric acid as a chiral synthon

✍ Scribed by Hiroaki Takayama; Masayuki Ohmori; Sachiko Yamada


Publisher
Elsevier Science
Year
1980
Tongue
French
Weight
149 KB
Volume
21
Category
Article
ISSN
0040-4039

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Vitamin D3 is known to undergo functional metabolism first in the liver, resulting in 25, hydroxy vitamin D3 which is transformed latter in the kidney to la,25-and 24(R),25\_dihydroxy vitamin D 3, both hormonally active in calciumhomeostasis.' The activity of D2 in mammals