Synthesis and cytotoxicity of a biotinyl
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Yuqiang Wang; Huiling Yuan; Susan C Wright; Hong Wang; James W Larrick
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Article
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2002
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BioMed Central
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English
โ 200 KB
Background: The use of pretargeting technology for cancer imaging and treatment has made significant progress in the last few years. This approach takes advantage of the fact that biotin binds strongly to proteins avidin and streptavidin. Thus, a non-toxic tumor cell specific antibody is conjugated