Synthesis and cytotoxic activity of a-ri
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Young-Jae You; Yong Kim; Nguyen-Hai Nam; Byung-Zun Ahn
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Article
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2003
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Elsevier Science
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English
β 176 KB
New A-ring modified betulinic acid derivatives having small steric hindrance were prepared and tested for cytotoxic activity on 3 cancer cell lines: 10 compounds showed stronger cytotoxic activity than betulinic acid. Especially, the compounds bearing 1-ene-3-oxo with electron-withdrawing groups at