𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of a bicyclic γ-lactam dipeptide analogue

✍ Scribed by Jack E. Baldwin; Christopher Hulme; Alison J. Edwards; Christopher J. Schofield; Kevin E.B. Parkes

Publisher
Elsevier Science
Year
1993
Tongue
French
Weight
257 KB
Volume
34
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis of a novel bicyclic γ-lactam a
Synthesis of a novel bicyclic γ-lactam analogue of the 1-oxapenams
✍ Jack E. Baldwin; Richard T. Freeman; Christopher Schofield 📂 Article 📅 1989 🏛 Elsevier Science 🌐 French ⚖ 139 KB

A succinct synthesis of a new bicyclic y-lactam designed to possess antibacterial activity containing an oxazolidine ring is described.

γ-Lactam analogues of carbapenems
γ-Lactam analogues of carbapenems
✍ D.B Boyd; B.J Foster; L.D Hatfield; W.J Hornback; N.D Jones; J.E Munroe; J.K Swa 📂 Article 📅 1986 🏛 Elsevier Science 🌐 French ⚖ 216 KB

Y-Lactam analogues of carbapenems have been synthesized using a [3+2] cyclisation approach. Slight antibiotic activity was observed in one case. S-Lactam antibiotics' mechanism of action involves active site acylation of key enzymes (penicillin binding proteins\_PBP's) required for bacterial cell wa

A γ-lactam analogue of penems possessing
A γ-lactam analogue of penems possessing antibacterial activity
✍ Jack E Baldwin; Christopher Lowe; Christopher J Schofield; Eun Lee 📂 Article 📅 1986 🏛 Elsevier Science 🌐 French ⚖ 239 KB

The synthesis of a Y-lactam analogue of the penems, which showed antibacterial activity, is described.

Synthesis of 6,5-fused bicyclic lactams
Synthesis of 6,5-fused bicyclic lactams as potential dipeptide β-turn mimetics
✍ Rudolf Mueller; Laszlo Revesz 📂 Article 📅 1994 🏛 Elsevier Science 🌐 French ⚖ 171 KB

The flmt short syntheds of the @eptIde mimetic (3s. 8S. SS)-8-amlnc-6-oxctndotiridiW-cafhoxyfk add 1 and its zpmtected dedvatlve 9 is described, empkyfng the Schoallkcpf bkkctim-ether methodokgy, folkwed by a highly specific lntramokcufar reductive afnfnatkn and spontaneous kctamizatlon. These W-fus