The enantioselective synthesis of the lactone moiety of (+)-compactin and (+)mevinolin was established starting from a meso-3,5-dihydroxycyclohexanone derivative by employing an enantioselective deprotonation strategy. (~
โฆ LIBER โฆ
Synthesis of 6-Aryl-4-hydroxypiperidin-2-ones and a Possible Applications to the Synthesis of a Novel HMG-CoA Reductase Inhibitor
โ Scribed by B. Taylor, John; J. Ashton, Michael; J. Hills, Susan; G. Newton, Chriastpher; C. D. Tondu, Sylvie
- Book ID
- 121659302
- Publisher
- Japan Institute of Heterocyclic Chemistry
- Year
- 1989
- Tongue
- English
- Weight
- 486 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0385-5414
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