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Synthesis of 5-methylthioribose specifically bitritiated at the 5-C position

✍ Scribed by Christina Viegas; Qiang Zhang; Danielle Guillerm; Georges Guillerm

Publisher
John Wiley and Sons
Year
2001
Tongue
French
Weight
98 KB
Volume
44
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

An efficient and reliable method for the preparation of bitritiated‐methylthioribose from a suitably protected 5‐ketoazido‐ribose derivative has been developed. This compound is an essential component in the assay of the microbial enzyme methylthioribose kinase, which is involved in the methionine salvage pathway from methylthioadenosine. Copyright © 2001 John Wiley & Sons, Ltd.

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