Synthesis of 5-Azacytidine Nucleosides with Rigid Sugar Moiety as Potential Antitumor Agents

ChemInform Abstract: Synthesis of Novel

ChemInform Abstract: Synthesis of Novel 3′-Deoxy-3′-C-hydroxymethyl Nucleosides with Conformationally Rigid Sugar Moiety as Potential Antiviral Agents

✍ Moon Woo Chun; Myung Jung Kim; Un Hee Jo; Joong Hyup Kim; Hee-Doo Kim; Lak Shin 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 26 KB 👁 2 views

ChemInform Abstract: Synthesis of New Nu

ChemInform Abstract: Synthesis of New Nucleoside Analogues Comprising a Geminal Difluorocyclopropane Moiety as Potential Antiviral/Antitumor Agents.

✍ Yao-Ling Qiu; Jiri Zemlicka 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Synthesis and conformational analysis of

Synthesis and conformational analysis of pyrimidine nucleoside analogues with a rigid sugar moiety

✍ Magnus Björsne; Tomas Szabó; Bertil Samuelsson; Björn Classon 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 563 KB

In order to obtain rigidity within the sugar moiety of nucleosides, some bicyclic pyrimidine nucleoside analogues were synthesized starting from cyclopentanone. The C-3' is fused to C-4' via a propylene linker in order to obtain a [3.3.0]-bicyclic ring system wherein the sugar moiety should be restr

ChemInform Abstract: Synthesis of Some 5

ChemInform Abstract: Synthesis of Some 5′-Thiopentofuranosylpyrimidines as Potential Antitumor Agents.

✍ F. GIRARD; S. LEONCE; L. A. AGROFOGLIO 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 1 views

Synthesis of Some 5'-Thiopentofuranosylpyrimidines as Potential Antitumor Agents. -The synthesis of 5'-sulfur-substituted thymidine analogues is achieved by nucleophilic displacement of the 5-chloro derivative (II) and subsequent oxidations and catalytic hydrogenations. None of these compounds show

ChemInform Abstract: Synthesis of Nucleo

ChemInform Abstract: Synthesis of Nucleosides Having Unusual Branched Sugars as Potential Antiviral Agents

✍ Kuniki Kato; Shosuke Yamamura 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 24 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Synthesis and molecular docking study of

Synthesis and molecular docking study of novel coumarin derivatives containing 4,5-dihydropyrazole moiety as potential antitumor agents

✍ Xin-Hua Liu; Hui-Feng Liu; Jin Chen; Yang Yang; Bao-An Song; Lin-Shan Bai; Jing- 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 316 KB

A series of novel coumarin derivatives containing 4,5-dihydropyrazole moiety as potential telomerase inhibitors were synthesized. The bioassay tests show that compound 3d exhibited potentially high activity against human gastric cancer cell SGC-7901 with IC(50) value of 2.69 ± 0.60 μg/mL. All title

Synthesis of 5-Azacytidine Nucleosides with Rigid Sugar Moiety as Potential Antitumor Agents

✦ Synopsis

Abstract