Synthesis of 5-[3-(diphenylphosphinoyl)propyl]-2-thiobarbituric acid
β Scribed by A. N. Reznikov; N. K. Skvortsov
- Book ID
- 111459563
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 95 KB
- Volume
- 78
- Category
- Article
- ISSN
- 1070-3632
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## Abstract A sodium derivative of 1,3βdimefhylbarbituric acid or 1,3βdiethylβ2βthiobarbituric acid undergoes an efficient monoacylation at C5 by the reaction with Οβchloroalkanoyl chloride or diacid dichloride in the presence of pyridine in tetrahydrofuran. A nucleophilic displacement of the chlor