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Synthesis of 4-oxo-2-azetidineacetic acids by means of radical cyclization of N-vinylic α-bromo amides

✍ Scribed by Hiroyuki Ishibashi; Kazuya Kodama; Chisato Kameoka; Hirotaka Kawanami; Masazumi Ikeda


Book ID
107857977
Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
977 KB
Volume
52
Category
Article
ISSN
0040-4020

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ChemInform Abstract: Total Synthesis of
✍ Masazumi Ikeda; Shinji Ohtani; Tatsunori Sato; Hiroyuki Ishibashi 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views

Total Synthesis of (-)-γ-Lycorane Using Diastereoselective 5-endotrig Radical Cyclization of N-Vinylic α-Halo Amides. -Radical cyclization of the acetamides (IV) proceeds with only moderate diastereoselectivity. Major product (Va) is converted to the title alkaloid (XI). -