Synthesis of 3,5-Dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl Containing 1,2,3-Thiadiazole Derivatives via Ugi Reaction and Their Biological Activities
โ Scribed by Shouxin Wang; Huan Wang; Prof. Dr. Zhijin Fan; Yifeng Fu; Na Mi; Jufang Zhang; Zhengcai Zhang; Nataliya P. Belskaya; Vasiliy A. Bakulev
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 101 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0256-7660
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Thermal reactions of 3-phenyl-5-arylamino-1,2,4-oxadiazoles I and II were investigated. Neat heating at ca. 250ะC for 6 hours afforded H 2 O, benzonitrile, arylcyanamides, arylamines, azobenzene, benzimidazole derivatives, and 3,3ะ-diphenyl-5,5ะ-bis[1,2,4-oxadiazolyl]. Analogous results were obtaine