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Synthesis of 3,3-(14C)-dimethyl-1-phenyltriazene from 14C-dimethylamine hydrochloride and benzene-diazonium fluoroborate

✍ Scribed by G. F. Kolar; Ch. Schweickhardt

Publisher
John Wiley and Sons
Year
1975
Tongue
French
Weight
286 KB
Volume
11
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

3,3‐(^14^C)‐Dimethyl‐1‐phenyltriazene was prepared from recrystallized benzenediazonium fluoroborate which was coupled with ^14^C‐dimethylamine in excess aqueous sodium carbonate at 0°. The crude product was extracted with ether and purified by distillation. Redistilled ^14^C‐labelled triazene was obtained in good yield (70.4 and 73.5%) and in high radiochemical purity (better than 99.9% by scan of thin‐layer chromatograms). The specific activities of two preparations, determined by liquid scintillation counting and corrected for quenching, were 244 and 296 μCi/mmole. The determined activities were in close agreement with values computed from the specific activity of ^14^C‐dimethylamine hydrochloride used in the synthesis.

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