𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of 3-indolyl(1-14C)acetic, 3-indolyl(2-14C) acetic and 3-indolyl(1,2-14C2)acetic acids

✍ Scribed by K. V. Viswanathan; T. V. Ramaamurthy


Publisher
John Wiley and Sons
Year
1980
Tongue
French
Weight
208 KB
Volume
17
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

The synthesis of 3‐indolylacetic acid labelled with ^14^C in side chain carbon atoms has been effected using (1‐^14^C)glycolic acid, (1,2‐^14^C~2~)glycolic acid and (2‐^14^C)glycolic acid in an yield of 40‐60%. Some of the parameters that affect the synthesis have been studied and the results are reported in this paper.


📜 SIMILAR VOLUMES


Synthesis of 14C-labeled halogen substit
✍ Bruce G. Baldi; Janet Pernise Slovin; Jerry D. Cohen 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 French ⚖ 254 KB

## Abstract A general method for microscale synthesis of ^14^C‐labeled indole‐3‐acetic acids with halogen substitutions in the benzene ring is described. The method utilizes halogen substituted phenylhydrazines reacted with [^14^C]‐2‐oxoglutarate to generate the halogenated indole‐3‐acetic acid. 3‐

Synthesis of homovanillic acid-2−14C, ho
✍ A. A. Liebman; D. H. Malarek; A. M. Dorsky; H. H. Kaegi 📂 Article 📅 1971 🏛 John Wiley and Sons 🌐 French ⚖ 493 KB

Specifically labelled phenylacetic acid and mandelic acid derivatives, metabolites of L-Dopa, have been synthesized via the intermediary labelled benzyl alcohols, which were prepared by reduction of the methyl esters of the appropriate benzoic acids. The benzyl alcohols have been converted to the co

Synthesis of N-(2-piperidylmethyl)-2,5-B
✍ E. H. Banitt; G. J. Conard 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 281 KB

## Abstract N‐(2‐Piperidylmethyl)‐2,5‐bis(2,2,2‐trifluoroethoxy)benzamide acetate (flecainide acetate; R‐818), a new antiarrhythmic agent, was labelled with carbon‐14 at the carboxamide position for metabolic studies. A three‐step synthetic route starting from 2,5‐dihydroxybenzoic acid‐carboxyl‐^14

Radiosynthesis of C-11 labeled auxin (3-
✍ Alicia E. Reid; Sung Won Kim; Brienne Seiner; Frank W. Fowler; Jacob Hooker; Ric 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 193 KB

## Abstract 3‐Indolylacetic acid (IAA) is the major auxin in higher plants and plays a key role in plant growth and development. We report the rapid radiolabeling of the important plant hormone using carbon‐11 (half life: 20.4 min) enabling __in vivo__ imaging of its distribution and movement in wh

Synthesis of malondialdehyde-1,2,3-14C3
✍ Michael J. Bienkowski; Melissa A. Tuttle; Lawrence J. Marnett 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 French ⚖ 234 KB

## Abstract The synthesis of 1,1,3,3‐tetraethoxypropane‐1,2,3‐^14^C~3~ from uniformly labeled paraldehyde is described. The synthesis involves three steps and proceeds in an overall yield of 25%. The final product is greater than 95% radiochemically pure and it is stable indefinitely when stored as