Synthesis of 3'-cyano-2',3'-dideoxyadenosine and 2',3'-dideoxy-3'-formyladenosine
β Scribed by Yu, Dong; D'Alarcao, Marc
- Book ID
- 120368238
- Publisher
- American Chemical Society
- Year
- 1989
- Tongue
- English
- Weight
- 453 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0022-3263
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The synthesis and antiviral evaluation of 2',3'-dideoxy and 2',3'-didehydro-2',3'-dideoxy 4'thionucleosides in both enantiomeric series are described. Enantiomeric 4-O-silylated-4hydroxymethyl-4-thiobutyrolactones, produced in high yield from chiral glycidols, provided suitable chiral synthons: phen
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