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Synthesis of 2′,3′-dideoxy-2′,3′-α-methanocytidine

✍ Scribed by Andrew R. Beard; Paul I. Butler; John Mann; Neil K. Partlett


Book ID
107725930
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
342 KB
Volume
205
Category
Article
ISSN
0008-6215

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Synthesis of tritium-labeled 2′,3′-dideo
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5 0 -O-Benzoyl-2,3 0 -anhydrothymidine. 60% Methanol in water, retention time 13.1 min. \* 2 0 ,3 0 -Dideoxy-2 0 ,3 0 -didehydrothymidine. Solvents: A -water; B -methanol. Program: 0-40% B/A in 40 min, retention time 33.9 min. TLC was carried out on Silufol plates (Czech Republic). \* 5 0 -O-Benzo