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Synthesis of 3′-, 4′- and 6′-deoxy and other analogues of d-glucosaminylphosphatidylinositol

✍ Scribed by Charles N Borissow; Terry K Smith; Michael A.J Ferguson; John S Brimacombe

Book ID
104211445
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
80 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

Deoxy and other analogues of D-glucosaminylphosphatidylinositol 1 have been synthesised and tested as substrates or inhibitors of a de-N-acetylase and mannosyltransferase (MT-1) involved in the biosynthesis of the glycosylphosphatidylinositol (GPI) membrane anchor of the parasite Trypanosoma brucei.

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