Synthesis of 3-deoxy-3-fluoro-d-mannose and 4-deoxy-4- fluoro-d-mannose
โ Scribed by James R. Rasmussen; Sherrie R. Tafuri; Stephen T. Smale
- Book ID
- 108309215
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 592 KB
- Volume
- 116
- Category
- Article
- ISSN
- 0008-6215
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Condensation of Z-deoxy-~-ribose with nitromethane gave, after deionization, a syrupy mixture of epimeric l-nitro-1,3-dideoxy-hexitols. Acid hydrolysis under Nef reaction conditions produced a mixture of 3-deoxy-~-glucose and 3-deoxy-m mannose, separable by cellulose chromatography or fractional cry
## Abstract A convenient method for the synthesis of ^18^Fโ2โdeoxyโ2โfluoroโDโglucose (4) and ^18^Fโ2โdeoxyโ2โfluoroโDโmannose (8) by the direct fluorination of 3,4,6โtriโ0โacetylโDโglucal with ^18^FโF~2~ is described. ^14^Cโ2โdeoxyโ2โfluoroโDโglucose has been synthesized from ^14^Cโ3,4,6โtriโ0โace