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Synthesis of (2RS,4'R,8'R)-.alpha.-tocopherol and related compounds via a 2-chlorochroman.

โœ Scribed by Cohen, Noal; Schaer, Beatrice; Scalone, Michelangelo


Book ID
127363160
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
479 KB
Volume
57
Category
Article
ISSN
0022-3263

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## Abstract The hydroperoxy endoperoxide **3**, obtained by photooxygenation of isotetralin (=โ€‰1,4,5,8โ€tetrahydronaphthalene; **1**), was reduced with thiourea, and the resulting intermediate **4** was converted, after acetylation with acetyl chloride, to the interesting, doubleโ€chlorinated acetate