✦ LIBER ✦

Studies on the total synthesis of (2R, 4'R, 8'R)-.alpha.-tocopherol (vitamin E). Stereospecific cyclizations leading to optically active chromans

✍ Scribed by Cohen, Noal; Lopresti, Rocco J.; Neukom, Christian

Book ID: 126057232
Publisher: American Chemical Society
Year: 1981
Tongue: English
Weight: 780 KB
Volume: 46
Category: Article
ISSN: 0022-3263
DOI: 10.1021/jo00325a004

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Stereocontrolled Generation of the (2 R

Stereocontrolled Generation of the (2 R ) Chroman Core of Vitamin E: Total Synthesis of (2 R ,4′ RS ,8′ RS )-α-Tocopherol

✍ Hernández-Torres, Gloria; Urbano, Antonio; Carreño, M. Carmen; Colobert, Franc 📂 Article 📅 2009 🏛 American Chemical Society 🌐 English ⚖ 485 KB

New Approach to the Synthesis of (2RS,4"

New Approach to the Synthesis of (2RS,4"R,8"R)-α-Tocopherol (Vitamin E)

✍ Odinokov, V. N.; Mallyabaeva, M. I.; Spivak, A. Yu.; Emel'yanova, G. A.; Dzhemil 📂 Article 📅 2001 🏛 Springer 🌐 English ⚖ 37 KB

Studies on the Synthesis of (2R,4′R,8′R)

Studies on the Synthesis of (2R,4′R,8′R)-α-Tocopherol Alternative Syntheses of 2-Chroman-acetic Acid Intermediates

✍ Noal Cohen; John W. Scott; Fred T. Bizzaro; Rocco J. Lopresti; Wayne F. Eichel; 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 German ⚖ 523 KB

## Abstract As an extension of previous studies on the total synthesis of (2R,4′R,8′R)‐α‐tocopherol (**1**) [1] [2], (S)‐(−)‐2‐(6‐benzyloxy‐2,5,7,8‐tetramethylchroman)acetic acid (**6**), a pivotal intermediate, possessing the absolute configuration required for construction of **1** was prepared b